Hydrochlorothiazide is a drug that excretes the excessive liquid from the body. This is an intensive diuretic that has a long-term action. Diuresis develops gradually and is not so intensive like Furosemide causes, but the action is softer, and therefore using Hydrochlorothiazide the side effects appear seldom.


Hydrochlorothiazide is used in two cases: exacerbation of arterial hypertension (high blood pressure), and edematic syndrome. And the edematic syndrome may be caused by the various disorders in the body: chronic renal failure, heart failure, pulmonary or brain edema, etc..


A therapeutic effect occurs in an hour after the use, and it reaches the maximum in 2-3 hours. The action lasts longer in comparison with Furosemide – about 12 hours. Therefore, you do not have to take pill often.


In what dose is Hydrochlorothiazide used?

To lower the blood pressure, Hydrochlorothiazide is taken in the dose of 25-50 mg a day. Diuresis starts in the first day of the use but it is not so intensive as next days.


Increasing the doses up to 100 mg enhances diuresis and reduces edema. The adjustment of the dose will help to regulate the volume of the liquid in the body.


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  • Elder people should take 12,5 mg Hydrochlorothiazide 1-2 times a day
  • Children at the age of 6 tom 14 take 1 mg per 1 kg body mass



As a maintaining therapy, Hydrochlorothiazide is taken not more than 2 times per week. If edema syndrome is increased, Hydrochlorothiazide is taken up to having the required result.



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  • The activity of diuretic and hypotensive products is increased. If you have a combined hypotensive therapy, lower the dose of both drugs
  • Do not take Hydrochlorothiazide during low blood pressure (even if you have severe edema)
  • As Hydrochlorothiazide enhances the production of important minerals, this medicine is not recommended during pregnancy and lactation
  • The use of Hydrochlorothiazide is contraindicated during ischemic heart disease, renal/hepatic insufficiency, and cerebral circulation disorder



Undesirable effects

Weakness, fatigue, drowsiness, anxiety, headache, dizziness, decreased libido, a sharp drop in blood pressure, muscle cramps are the symptoms occurring within the first several uses of the drug. Usually these symptoms are reduced during the regular use of the pills. But if they grow, stop the treatment. Do not take Hydrochlorothiazide if you feel that it does not work for you.


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